Protocole Transition Hormonale Cutanée

Hormonal Transition Protocol

Skin in Perimenopause

Developed specifically for skin undergoing hormonal transition:

Physiological pH (~5), free from endocrine disruptors, and compatible with any gynecological or hormonal treatment.

The drop in estrogen simultaneously triggers a slowdown in fibroblast activity, a decrease in ceramides, reduced sebum production, and a gradual thinning of the skin barrier.
At the onset of menopause, collagen synthesis can decline by up to 30 %.

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A Gradual Reconstruction of Hormonal Transition

Aquaporin‑3 channels, essential for water transport and retention in the epidermis, become impaired.
The skin progressively loses its natural ability to maintain hydration and structural density.
This is not simple dryness, but a systemic biological event requiring a structured clinical response: formulations with physiological pH (~5), free from endocrine disruptors, and compatible with any gynecological or hormonal care.
The skin must be rebuilt and strengthened progressively.

Step 01 · Morning & Evening

N°1 — Ultra‑Gentle Facial Cleanser Light gel · pH 5 – Cleanses without altering the hydrolipidic film weakened by estrogen decline.Amino‑acid‑based, eco‑sourced surfactant. Essential lipid contribution for hormonally dehydrated skin.Zero delipidation of the skin barrier. Full respect for the physiological acid mantle. Key actives: Disodium Cocoyl Glutamate · Inulin · Polyglyceryl‑3 Caprylate

Step 02 · Evening

N°5 — Night Reconstruction Serum Designed to reactivate biological hydration, repair the extracellular matrix, and restore skin elasticity.Regeneration & Collagen. Collagen I synthesis superior to conventional retinoids = +34 % elasticity after 42 days (Cutometer). Repairs the extracellular matrix. Stimulates cell proliferation. Promotes fibronectin. Targeted anti‑inflammatory action.Key actives: Inulin · Sodium Retinoyl Hyaluronate · Sodium Hyaluronate

Step 03 · Morning & Evening

N°6 — Hydrating Facial Lotion Velvety‑light fluid · pH 5 – Hydrates, soothes, and protects against hormonal aging.Key actives: Inulin (+20 % hydration, −21 % TEWL) · Beta Glucan (soothing, immune support) · Haematococcus Pluvialis (antioxidant, anti‑inflammatory protection)

Step 04 · Morning – Before Exposure · Every 45 Minutes

N°7 — Protective Defense Mist Ultra‑light mist · pH 5 – Multifactorial anti‑aging protection.−28 % pigmentation · +3 % radiance · −19 % wrinkle depth · −21 % wrinkle volumeUV protection for Langerhans cells. Collagen renewal & anti‑inflammatory defense.−30 % pollution‑induced inflammation.Free from endocrine disruptors.Key actives: Ectoine · Natural Polysaccharide · Protective Complex = support for the skin’s antioxidant defenses